| Drug Name |
XIFAXAN |
| Active Ingredient(s) |
RIFAXIMIN |
Form(s) and
Strength(s) Available |
TABLET; ORAL |
Product Information / Press Release Xifaxan is a nonsystemic (less than 0.4% of the drug absorbed into the bloodstream), gastrointestinal-selective, oral antibiotic.
Xifaxan (rifaximin) tablets are indicated for the treatment of patients (12 years of age and older) with travelers' diarrhea caused by noninvasive strains of Escherichia coli. Xifaxan should not be used in patients with diarrhea complicated by fever or blood in the stool or diarrhea due to pathogens other than Escherichia coli. Xifaxan should be discontinued if diarrhea symptoms get worse or persist more than 24-48 hours and alternative antibiotic therapy should be considered.
In clinical trials, Xifaxan was generally well tolerated. The most common side effects (vs. placebo) were flatulence 11.3% (vs. 19.7%), headache 9.7% (vs. 9.2%), abdominal pain 7.2% (vs. 10.1 %) and rectal tenesmus 7.2% (vs. 8.8%).
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